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Here’s what you need to know about Preimplantation Genetic Diagnosis (PGD)

Preimplantation genetic diagnosis (PGD) is a type of genetic testing performed during IVF that detects single-gene disorders in embryos. PGD allows couples with a hereditary genetic condition such as sickle cell anemia to significantly reduce the risk of passing it onto their children.

It may be recommended for individuals with a family history of certain genetic conditions.

If there is a genetic condition present in your family, (for instance AS/AS couples) you may want to explore options to reduce the risk of passing the condition on to your baby.

Therefore, your fertility doctor may bring up the option of PGD testing.

PGD followed by the sex selection of embryos for transfer can also be used for pre-pregnancy and pre-birth sex selection of babies. With improvements in gender selection technology, demand for gender selection has also been growing steadily.

Indications for PGD

– Recurrent Miscarriage

– Unsuccessful IVF Cycles (>2)

– Unexplained Infertility

– Advanced Maternal Age

– Male Factor Infertility

– History of Chromosomally Abnormal Child or Pregnancy

– Family history of structural chromosomal condition

– Family history of X-linked disease

– Inherited genetic disorders

The PGD Testing Cycle

Step 1: Stimulation of the Ovaries

Step 2: Egg Collection

Step 3: Fertilization

Step 4: Culture and Biopsy

Step 5 PGD Testing

Step 6: Embryo Transfer

Step 7: Pregnancy test

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